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10.2337/db14-0849 [DOI] [PubMed] [Google Scholar] Varin, E

On the other hand, RWE lacks the ability to establish causality by minimising confounding effects which is a key strength of randomised clinical trials (RCTs)

J Am Stat Assoc

A combination approach to precision prevention that follows a brain health optimization framework could involve sequential interventions such that relatively low-risk NPIs are implemented earlier in the life course

M., Parker, R

That is a recipe for problems
