2024 asa guidance glp-1 receptor agonists perioperative How should we approach patients on agonists? Check out this excellent editorial from Dr. Girish Joshi, "Clarifying the Guidelines and Decoding the Enigma: Strategies for Anesthetic Management of Patients on Glucagon-Like Glucagon-like peptide-1 receptor agonists as

Future research should focus on longitudinal dietary assessment, biomarker monitoring, and validation of standardized nutrition protocols for patients receiving GLP1-based obesity pharmacotherapy.

Ozempic, Wegovy, Zepbound, and Mounjaro are GLP-1 medications that help lower blood sugar

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Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells that modulates glucose metabolism by controlling insulin excretion and glucagon secretion and inhibits gastric emptying leading to decreased food intake, thus limiting weight gain

This allows compound 2 to execute positive allosteric modulation through enhancement of both agonist binding and G protein coupling