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While not officially approved for weight loss, some doctors prescribe it off-label for that purpose.

![Figure][1] Graphical Abstract: ### Competing Interest Statement The FR + FMG laboratory receives funding from AstraZeneca, Eli Lilly and LGM for unrelated research and FMG consults for Kallyope (New York)

[Ayurvedic Triphala for Gentle Detox & Regularity] Includes a traditional Triphala fruit blendHaritaki, Bibhitaki, and Amla - used in Ayurveda to support gentle cleansing, healthy elimination, and natural digestive balance

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In the largest comparative effectiveness study of tirzepatide (Mounjaro) and semaglutide (Ozempic) for weight loss using real-world data now published in JAMA Internal Medicine Truveta Research found that patients with overweight or obesity taking tirzepatide were three times more likely to achieve 15% weight loss than those taking semaglutide