tirzepatide and cancer risk New research suggests GLP 1 medications like semaglutide tirzepatide, widely used for weight loss and diabetes, may also lower the of several obesity related cancers, including colorectal, endometrial, and breast Popular obesity medications significantly lower

GLP-1 may modulate lipid metabolism through increased sympathetic tone, leading to increased lipolysis, heightened triglyceride catabolism, and enhanced fatty acid oxidation (181)

As of mid-2025, retatrutide remains in clinical trials and has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)

But how do you navigate the silent nightmare of Christmas snacking if you are on semaglutide (Wegovy or Ozempic)

Modest weight loss (5% to 7%) and you absolutely cannot inject: Oral semaglutide is a reasonable option if you can commit to the dosing ritual

A larger percentagearound 35%see modest results (5-15% loss) rather than the dramatic 15%+ loss others achieve

Circulation 144 , 17951817 (2021)