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Simple adjustments such as drinking coffee after meals, reducing caffeine strength, improving hydration, or choosing lower-acid options may help improve comfort during treatment

NICE hasn't yet published guidance on the Wegovy pill, so NHS access may change in future

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Because tirzepatide and semaglutide have different receptor profiles, half-lives, and dose-response curves, there is no direct milligram-to-milligram conversion

Patients with certain GLP1R variants may experience stronger appetite suppression at lower doses, suggesting a more gradual progression works better