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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Mostafa NM, Nader AM, Noertersheuser P, Okun M, Awni WM

Here is what it is, how the 2024 FDA shortage change affects availability, how it is dosed, and who qualifies, from a supervised clinic in Doral

People can get serious electrolyte disturbances that can lead to heart arrhythmia and death from laxative abuse. Laxatives like Miralax are safe to use long-term for constipation management in people who are constipated, but abusing them in order to produce weight loss is medically and psychologically dangerous. Despite potential side effects from laxatives and stool softeners, some people have made the switch after they stopped taking weight-loss drugs such as Ozempic and Wegovy due to extreme side effects

Obesity pharmacotherapy from the @TheAACE diabetes algorithm: GLP1/GIP and GLP1 RAs produce ~1020% weight loss with A1c reduction, while older agents like phentermine, orlistat, and naltrexone/bupropion have less efficacy and safety tradeoffs

Side effects of these weight loss medications include nausea, diarrhea, and vomiting

This means you naturally eat less without feeling deprived