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In trials, average results were strong, but people did not all lose the same amount of weight or get the same level of glucose improvement

Currently, nearly 100 million people globally are affected by DR, and as the prevalence of diabetes continues to rise, this number is expected to grow, posing a significant burden on public health (82)

Practice Pearls: Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of oral drugs for type 2 diabetes that inhibit the breakdown of glucagon-like peptide-1 (GLP-1) and increase the release of insulin in response to a meal

Dulaglutide has been shown in studies to cause thyroid tumors in animals, but it's not yet known if it can cause thyroid cancer in people

Hazard ratios (HRs) with 95% confidence intervals (CIs) were used to assess primary (MACE) and secondary outcomes (all-cause mortality, CV death, non-fatal MI, non-fatal stroke, and HF hospitalisation) between the two treatment groups

GLP-1 agonists are used to help manage type 2 diabetes and obesity as well as a few other conditions