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( H ) Intracellular cAMP accumulation in human caSMCs treated with the sAC inhibitor KH7 (25 M, dark gray bars), the tmAC inhibitor Ddox (50 M, white bars), or PBS (light gray bars) for 3 hours followed by a 15-minute treatment with GLP-1(2836), scrambled control, IPE, or forskolin

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Key facts: Medicaid launch : as early as May 2026 Participation : voluntary for states states must opt in Pricing : CMS negotiates directly with Eli Lilly (Zepbound/Mounjaro) and Novo Nordisk (Wegovy/Ozempic)