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The authors show that GIPR activation enhances entry of GLP-1R agonists into the brain, and this process depends on oligodendrocyte GIPR signaling

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The MN patch could load up to 2.210.14 mg of liraglutide in a patch size of 0.9 cm2, which was nearly two orders of magnitude higher than that obtained with conventional MN patches of the same size

p=0.29 vs placebo)