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The comparison between tirzepatide and next-generation triple agonists like retatrutide is relevant for researchers tracking the evolution of this field

Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP)

Psychiatrists 68 (1), e20

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This inhibits the activation of intestinal FXR signaling, thereby facilitating enhanced glucose homeostasis ( Changes in the gut microbiota caused by metformin are crucial for its ability to reduce inflammation
All treatments significantly elevated the serum levels of kynurenine, but they failed to affect the kynurenine-Trp ratio