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SNAC functions through a multifaceted mechanism: it buffers the local gastric pH, thereby protecting semaglutide from acidic degradation and proteolytic enzymes, and enhances drug solubility and monomerization

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Her diabetes regimen was transitioned to basal insulin (insulin glargine), metformin, and, later, Janumet XR (sitagliptin/metformin) and dapagliflozin, with ongoing continuous glucose monitoring (CGM)

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