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These medications also delay gastric emptying through neural mechanisms, increasing the risk for perioperative aspiration during anaesthesia and sedation

### Funding Statement SDL and AC were supported by the National Science Foundation (Grant Nos.\ CAREER DMS-1944574 and DMS-2325258) ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained
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Safety issues like the black box warning for thyroid cancer risk are also addressed

Eli Lilly and Company has announced Zepbound (tirzepatide) 2.5mg and 5mg single-dose vials are available for self-pay for patients with an on-label prescription, significantly expanding the supply of Zepbound in response to high demand

The researchers analyzed data from a large, multi-institutional medical records database, including 73,483 adults taking GLP-1sincluding Semaglutide drugs like Ozempic & Wegovy, as well as Victoza (Liraglutide), Trulicity (Dulaglutide), or Byetta (Exenatide)and compared them with the same number of adults not taking the medications, tracking health outcomes for five years after treatment began