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As your comfort level grows with successive injections, you may notice anxiety decreases and confidence in your self-administration technique improves

It means adapting your daily habits to work with your body's new digestive pace

doi:10.1016/S0140-6736(18)31924-X 12

A 2022 review in Nature Metabolism outlined the concept of receptor downregulation following sustained agonist exposure, a well-established pharmacological principle in which the body reduces its sensitivity to, and endogenous production of, a hormone when that hormone is chronically supplied externally

I think back to a year ago, and I was mentally and emotionally drained

If your system becomes overly sensitive to the presence of new food, it may overreact by trying to clear the colon quickly, resulting in post-meal urgency