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Is it advantageous to use quality by design (QbD) to develop nanoparticle-based dosage forms for parenteral drug administration

This is generally discouraged because the interaction is highly unpredictable

I discussed Ozempic as a sort of cultural shorthand earlier this year in Health Populi

Abstract Diabetic kidney disease (DKD) is a leading cause of end-stage kidney disease and significantly increases cardiovascular risk and mortality

Pariyar R, Bastola T, Lee DH, Seo J

In our study, liraglutide prevented the TGF-1 + IL-1-induced augmentation of mitochondrial respiration in fibroblasts, indicating that activating GLP-1R could maintain mitochondrial homeostasis under inflammatory stress