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To learn more, clinicians can review the latest ADA Standards of Care at diabetes.org
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Gastrointestinal symptoms remain the most common concern for new users in the Mounjaro vs Trulicity comparison
[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Joaqui VB, Gmez NB, Ortiz RC, et al

GLP-1RAs such as semaglutide are known to cross the bloodbrain barrier, suggesting that their pain-relieving effects could be mediated through brain structures such as the hypothalamus and brainstem, areas that regulate nociception [102]
