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GLP-1RA use was defined as having an active prescription for either semaglutide, dulaglutide, liraglutide, or tirzepatide in the electronic medical record

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Large randomized controlled trials including the STEP trials (Semaglutide Treatment Effect in People with obesity) did not separate outcomes by injection timing, because the drug's long half-life eliminates time-of-day variations

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Within the first year and beyond, GLP-1 weight-loss users change their spending habits significantly

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