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Description
Results: Of 969,240 patients with T2DM, 9.7% (93,608) were on GLP-1 RA, and 90.3% (875,632) were not
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Gastrointestinal adverse events were predominantly limited to initial dosing, while dose escalation resulted in lower discontinuation rates owing to these adverse events than among patients who remained on the starting dose

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Importantly, when researchers blocked the GLP-1 receptor by injecting its inhibitor into the joint, the protective effects disappeared
