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Sulfonylureas (SUs) and exogenous insulin, on the other hand, do not provide the same protection and may actually worsen cognitive outcomes

Tirzepatide is a dual agonist that targets both GLP-1 and GIP receptors, which is why clinical trials have shown even greater weight loss over 20% of body weight in some studies compared to semaglutide's average of 15%

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As competition intensifies in obesity, companies are increasingly looking for the next wave of high-value opportunities in adjacent metabolic and gastrointestinal diseases

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