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Comprehensively prognostic and immunological analyses of GLP-1 signaling-related genes in pan-cancer and validation in colorectal cancer

YAP/TAZ is sequestered in the cytoplasm through 14-3-3 protein binding and subsequently degraded by the proteasome (214)

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The global burden of overweight-obesity and its association with economic status, benefiting from STEPs survey of WHO member states: A meta-analysis
911 Although these findings provide insight into the potential relationship between GLP-1RAs and cancer risk, all existing studies have focused on comparisons among glucose-lowering drugs (GLDs) in patients with T2D, leaving uncertainty regarding their potential role in cancer prevention in individuals with obesity regardless of diabetes status

It is reported that ARR1 controls the desensitization of the GLP-1R