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The study is both relevant and timely, as it sheds light on a current issue in clinical practice

The guidelines assume some exposure, not constant exposure

The gradient for mitral valve inflow reflects the difference in wedge pressure and intra-cardiac chamber (LV) pressure
It is also used for weight reduction in overweight people (BMI of 27 or more) who have a comorbid condition like hypertension or type 2 diabetes mellitus

Sergey Terushkin, MD, FACS Key Takeaways Tirzepatide, marketed as Mounjaro, was initially developed for type 2 diabetes but has rapidly emerged as one of the most effective medications for medical weight loss

What makes Invokana special is that it does more than control blood sugar
