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Description
GLP-1 provides powerful appetite suppression through brain receptors

2018;78:315322.e1

82,83 However, it has not been elucidated if insulin is locally synthesised in the brain or if it is transported from circulation in order to mediate any effects

administration of the experimental compounds (MK-801, GLP-1, GLP-1MK-801 (all at doses of 100 nmol kg 1 ), semaglutide (10 nmol kg 1 ) or isotonic saline as vehicle)

13 The median expected protection we determined for GLP-1 receptor agonistswhich exceeds 18 yearsis the highest yet reported for drug-device combinations

Project administration: HSK
