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Common side effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and abdominal discomfort, particularly during the initial weeks of treatment

Weight loss yields reductions in total, visceral and pancreatic adipose tissue, reductions in intrahepatic levels of lipids, and improved insulin sensitivity, all of which are expected to improve systemic glucose metabolism 18

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In one such study, 68 weeks in duration, people given semaglutide injections lost an average of 15-20% of their total body weight

The Efficacy of GLP-1 Agonists in Treating Substance Use Disorder in Patients: A Scoping Review