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On the other hand, in vitro experiments demonstrated that GLP-1RA morroniside could act directly on primary microglia, and promote the mRNA levels of the M2 microglial cell markers Agr1, C206, IL-4, and IL-10

The American Diabetes Association (ADA) guidelines updated in 2023 recommend GLP-1 receptor agonists as a preferred treatment option for many patients with type 2 diabetes, particularly those with or at high risk for cardiovascular disease or kidney disease

Rabizadeh S, Nakhjavani M, Esteghamati A (2019) Cardiovascular and renal benefits of SGLT2 inhibitors: a narrative review

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She boasted of how she walked into a liquor store recently to buy a pack of American Spirit cigarettes and managed to walk out without even thinking of alcohol