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The SURMOUNT-5 trial (Aronne et al., NEJM 2025) showed that tirzepatide, a dual GIPGLP-1 receptor agonist, outperforms semaglutide in reducing weight and cardiometabolic risk in adults with obesity without diabetes
Medical experts and researchers are trying to understand if there is a real link between semaglutide and uterine bleeding.
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Starting at 241 lb, she lost 90 lb (over 30% of her body weight) over 65 weeks without side effects
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