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This risk was reduced even further in cases of prolonged treatment extending beyond three years (HR: 0.71), though GLP-1RA treatment for zero to one years (HR: 0.89) and one to three years (HR: 0.85) were not significant

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When to Contact Your Healthcare Provider About Leg Cramps Contact your prescriber if leg cramps become frequent (occurring multiple times daily), severely painful, or prevent sleep or daily activity

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