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It's mechanical, predictable, and critically manageable with the right habits

I can walk, cook, and feel like myself again

It is distinguished by synovitis, continuous joint inflammation, and a diverse range of systemic comorbidities [229, 230]

[10] [4] Kidney-related symptoms such as markedly reduced urine output, dark scant urine, or swelling in the legs may indicate acute kidney injury from dehydration and require urgent evaluation

In some cases, patients experience headaches or dizziness

For the second experiment (Fasting study): Mice were sacrificed after 16 h of fasting, and livers were collected and snap-frozen in liquid nitrogen until further processing