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Description
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the Western hemisphere, affecting 20% to 30% of the adult population [1]

Some patients tolerate oral semaglutide better than injections due to slower absorption patterns

Wegovy is the cheapest GLP-1 available without insurance, costing $149 a month for the pill and $349 a month for the injectable

25,26 Effects on Epicardial Adipose Tissue GLP1-RAs decrease the volume of epicardial adipose tissue, which is often elevated in HFpEF and is a source of proinflammatory cytokines and adipokines

The costs of research on innovation, safety of use, production, administration of the drugs, and distribution would be spread over a wide swathe of the population, via government initiative and funding, as the advantages would accrue to not only direct users but also the other segments of society

Bariatric Surgery ($15,000-$30,000) Cost: $15,000-$30,000 out-of-pocket (if insurance doesnt cover it) Effectiveness: High (60-70% excess weight loss on average) Verdict: Effective but expensive, irreversible, and comes with surgical risks and lifelong dietary restrictions
