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Researchers who use microdosing strategies to bridge between dose levels may not need this adjustment, but for those following standard escalation protocols, it is a valuable tool

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These details matter for your first dose and every dose after

Keep the needle pointing up and press the dose button until "0 mg" lines up with the pointer

Get rid of any air bubbles by tapping the syringe and putting slight pressure on the plunger until a drop of medication appears at the tip of the needle