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In a mouse model of 5-fluorouracilinduced mucositis, daily treatment with 3 nmol/kg tirzepatide for 7 days, but not 41 g/kg semaglutide, significantly reduced ileal neutrophil elastase staining (89)

61,92,93 Similarly, microglia, CNS-resident myeloid cells of embryonic origin that comprise 15% of all cells in brain, express GLP-1Rs

Recent news from the GLP-1 space highlights continued investment in next-generation therapies, late-stage clinical development, strategic partnerships and regulatory progress as the rapidly evolving space remains one of the most closely watched areas in healthcare and biotechnology
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