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Clinical audiences are equally impressed with the data, hailing a new era for how obesity is perceived and treated, notwithstanding the missed statistical significance for cardiovascular death and the other secondary confirmatory endpoints not being tested for superiority as a consequence

A sub-analysis comparing the two intervention cohorts was also performed

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Among these, pioglitazone and liraglutide seem to improve some histological features of NASH but have no clear effect on fibrosis