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Accumulation of methylglyoxal (MG) contributes to glucotoxicity and mediates beta cell apoptosis

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Human data (from a meta-analysis of 894 participants) show fenugreek supplementation (0.5 g to 10 g daily over 4 weeks to 6 months) reduces fasting glucose, post-meal glucose, and HbA1c

Understanding the science behind this dosing pattern helps explain why more frequent doses aren't necessary for effective weight management

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Some theories suggest semaglutide may affect the absorption of the birth control pill, but more research is necessary