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The cost-effectiveness calculation also depends on treatment duration

Mike Haney: You did something with this book that I wish all books that were trying to present a solution to obesity had to do, which is you came up with the idea and then you ran a study to validate it, and then you wrote the book about it

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Compared to twice-daily preclinical dosing with the GLP-1 analogue liraglutide, once-weekly dosing of ZP4982 at almost equimolar doses was superior in terms of body weight loss in an obese rat model (143)