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[DOI] [PubMed] [Google Scholar] 88.Friedrichsen BN, Neubauer N, Lee YC, Gram VK, Blume N, et al

Each dose increase typically brings a temporary return of side effects as the body adjusts to higher drug levels

However, Retatrutide is not yet Health Canada approved, with expected regulatory decisions coming in late 2026 or early 2027

If severe symptoms developincluding difficulty breathing, chest pain, severe nausea or vomiting, or altered consciousnessseek emergency medical care immediately

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