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Tamborlane WV, Barrientos-Perez M, Fainberg U, Frimer-Larsen H, Hafez M, Hale PM, et al
J Clin Endocrinol Metab 2025
Where the GLP-1 medication assists with blood sugar management at mealtimes, making lifestyle adaptations goes together
In the STEP 1 trial published in Diabetes, Obesity, and Metabolism , participants who paired weekly semaglutide for weight loss with a structured lifestyle intervention regained an average of two-thirds of the weight theyd lost within one year after stopping both
The appeal is strongest among middle-aged Americans dealing with weight gain and obesity-related health conditions
Discontinuation rates due to adverse events ranged from 12.2% to 18.2% across dose groups
