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Therapeutic Strategy: Targeting the GMGLP-1 Axis The authors propose a multi-level intervention framework that moves well beyond GLP-1RA pharmacotherapy alone: Lifestyle foundation : Diet and exercise modulate GM composition, enhance SCFA and bile acid production, and raise endogenous GLP-1 levels simultaneously addressing all four disease processes

doi: 10.1007/s11102-022-01297-x 146 TaghaviSMFatemiSSRokniH

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