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Assessment of thyroid carcinogenic risk and safety profile of GLP1-RA semaglutide (ozempic) therapy for diabetes mellitus and obesity: a systematic literature review

Expect a brief transition period where appetite suppression may temporarily decrease before tirzepatide effects build

Ongoing trial extensions and postmarketing data continue to clarify the durability of outcomes

Also be aware of long-term safety questions and make sure your provider is monitoring you carefully

Table of Contents Mechanism of action of GLP-1 The emerging clinical research and drug marketing Wegovy and Ozempic, side-by-side Side effects and adverse events Current anesthesia care guidance on patient care Summary of where we are Mechanism of action of GLP-1 GLP-1 is a hormone inactivated by the enzyme DPP-4

doi: 10.1073/pnas.0806720106 [DOI] [PMC free article] [PubMed] [Google Scholar] 109
