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These medications, like phentermine or semaglutide , are FDA-approved and can help suppress appetite

Compounded tirzepatide contains the same active ingredient as Zepbound but is not FDA-approved and does not undergo the same quality control testing

Through acceptance of this federal funding, the NIH has been given a right to make the work publicly available in PubMed Central

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How GLP-1 Medications Target Addiction Pathways in the Brain GLP-1 receptors are distributed throughout multiple brain regions, including areas associated with reward, motivation, and decision-making

Additionally, weight loss itself enhances insulin sensitivity, creating a synergistic effect