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Yacon syrup is a prebiotic fiber that can cause some digestive discomfort in some people
GLP-1 receptor agonist exenatide uncouples food intake from hedonic and anticipatory regulation in non-human primates: insights from an operant meal schedule paradigm
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10.1161/CIRCULATIONAHA.107.739938 [DOI] [PubMed] [Google Scholar] 10

STEP-4 gave every participant a 20-week course of semaglutide 2.4 mg once weekly, and produced a mean weight loss of 10.6%, before randomisation to either continued semaglutide treatment or exchange to placebo for an additional 48 weeks