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Palpitations often come from triggers like caffeine, stress, or intense exercise

At 48 weeks, the least-squares mean percentage change in body weight in the retatrutide groups was -8.7% (1 mg), -17.1% (combined 4 mg), -22.8% (combined 8 mg), and an astounding -24.2% (12 mg), compared to -2.1% in the placebo group
Phase 2 used aggressive titration

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Changes in glucose homeostasis after Roux-en-Y gastric bypass surgery for obesity at day three, two months, and one year after surgery: Role of gut peptides

Monami et al evaluated changes in lipid levels with GLP-1RA versus placebo in a meta-analysis
