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This occurs through the phosphorylation of myosin light chain (MLC) by ROCK, resulting in cytoskeletal reorganization and changes in endothelial cell adhesion

Holt, James E

This is especially relevant for diseases like diabetes and obesity, which have worldwide prevalence

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Retatrutide: a peptide drug with three targets GLP-1R/GCGR/GIPR Retatrutide (LY3437943) is a peptide drug developed by Eli Lilly based on the GIP peptide sequence, targeting GLP-1R/GCGR/GIPR

doi: 10.3390/plants12142620