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While AOM tirzepatide has higher rates of prescriptions, its momentum slowed after the CVS formulary shift, just as AOM semaglutide shows potential renewed growth

Add resistance training : Two to three sessions per week targeting major muscle groups is the single most evidence-supported intervention for protecting your metabolism during a plateau

doi: 10.1111/j.1748-1716.2009.01970.x

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2 Search strategy and inclusion criteria This mini-review was based on a targeted literature search conducted in PubMed/MEDLINE and Scopus from January 2015 to August 2025, using the keywords GLP-1 receptor agonists, exercise, physical activity, obesity, type 2 diabetes, and weight loss. Additional terms ( lean mass, body composition, insulin sensitivity, cardiometabolic, combined intervention ) were used in secondary searches