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The relationship is bidirectional and more complex than most people realize

However, the financial impact of the reported decrease in cardiovascular events has not yet been established (39)

The impact has been extraordinary

In summary, current evidence clearly shows direct cardioprotective effects of GLP-1 and GLP-1RAs in preclinical models of heart failure (Figure 2)

Novo was first in the market,got CMS Medicare approval with Narrow Pipeline of Drugs only on Weight loss & Diabetes (Front runner Semaglutide) Lilly has better Efficacy Drug(Tirzepatide & Pipeline drugs) for Wt loss/Diabetes,Longer IP Patent Runway till mid 2030s with better Growth Penetration With Wider Pipeline of Pharma drugs including Oncology/ Neurology/ Immunology/ Inflammation,Urology- Erectile Dysfunction,Osteoporosis in Men and Women and afford to run the price war with Novo and wipeout their Business Eli Lilly is winning hands down

Ozempic, the medicine known generically as semaglutide, was approved by the U.S