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That covers: Fasting glucose (basal insulin) Post-meal glucose (GLP-1) Weight loss (GLP-1) Cardiovascular protection (GLP-1) The COMBINE Phase 3a trials have already shown superior HbA1c reduction with a lower insulin dose and non-inferior control vs
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There were no statistically significant interactions by treatment and background medication subgroup for change in HbA1c or body weight except for change in HbA1c (background insulin vs insulin plus metformin) in PIONEER 8 (p=0.0408)
Semaglutide results broken down honestly what 15%, 20%, and 30% body weight loss looks like in real numbers, real clothes sizes, and real energy levels.
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