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At present, this question remains biologically plausible but clinically unproven

While both fall under the umbrella of "incretin mimetics," their unique biological actions can produce very different outcomes

Walking and low-impact cardio are beneficial for cardiovascular health but do not provide sufficient osteogenic stimulus to meaningfully protect bone density during rapid weight loss

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Moreover, increased expression and secretion of both IL-1 and TNF- together are considered an alarm signal that initiates inflammatory responses by inducing a cascade of other pro-inflammatory genes

Cardiovasc Diabetol 13 , 142 (2014)