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[DOI] [PubMed] [Google Scholar] 212.Emslie-Smith A.M., Boyle D.I., Evans J.M., Sullivan F., Morris A.D., DARTS/MEMO Collaboration Contraindications to Metformin Therapy in Patients with Type 2 DiabetesA Population-Based Study of Adherence to Prescribing Guidelines

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That last point is easy to miss

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According to NICE guidance and MHRA safety information, healthcare professionals should maintain vigilance for rare but serious adverse effects including acute pancreatitis, gallbladder disease, and potential thyroid tumours (based on animal studies, though human risk remains uncertain)

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Funding This research was supported by grants from Kaohsiung Veterans General Hospital (KSVGH115-D01-1 and KSVGH115-D02-1), Taiwan

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