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Mechanism & Research Context Reference information for research documentation

Reduced levels of the mitochondrial autophagy-associated protein Parkin in the substantia nigra may contribute to the development of Parkinsons disease (PD) in db/db mice and high-fat diet-induced diabetic mice

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Healthy fats like avocados, nuts, seeds and olive oil can promote brain health, and hydrating foods like cucumbers and watermelon can help prevent dehydration

In this Perspective, we summarize data on cancer incidence from trials and registries in individuals with type 2 diabetes, describe the actions of GLP-1 medicines on preclinical cancer models and highlight possible direct and indirect mechanisms linking GLP-1R signaling to cancer development and progression