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Federal drug regulators on Wednesday moved to restrict a substance derived from the kratom plant and sold in gas stations and smoke shops thats drawn increasing concern from public health officials about its addictive potential.

A National Institutes of Health (NIH)-funded study has found that an emerging class of GLP-1 weight loss drugs suppress eating for pleasure, or hedonic feeding, in mice by modulating a reward circuit deep within the brain

The glucagon-like peptide-1 (GLP-1) receptor is a key regulator of glucose homeostasis and a drug target for type 2 diabetes but available GLP-1R agonists are suboptimal due to several side-effects

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