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[48] Pancreatic and thyroid safety [edit] Historically, GLP-1 receptor agonists have carried warnings regarding acute pancreatitis and pancreatic cancer

Psyllium husk (found in products like Metamucil) is a popular fiber supplement that provides both soluble and insoluble fiber to help soften and bulk up stool

Ji L, Jiang H, Cheng Z, et al

Graziano MP, Hey PJ, Borkowski D, Chicchi GG, and Strader CD

Several network meta-analyses have compared the efficacy of different GLP-1RAs.1718192021 However, the development of GLP-1RA novel drugs is indeed a rapidly evolving area, and many new drugs have emerged this year, including orforglipron, retatrutide, and CagriSema (semaglutide with cagrilintide)

Both groups also demonstrated significant improvements in triglyceride levels and high-density lipoprotein cholesterol (HDL-C) after 56 weeks [15]