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Bottom line: GLP-1 patches may contain recognisable ingredients, but there is currently no strong evidence that those ingredients are absorbed through the skin in amounts sufficient to support the effects claimed

For researchers and clinicians making decisions today, timeline matters as much as efficacy data

This article examines the science, safety considerations, and evidence-based alternatives for patients considering GLP-1-related therapies

However, given the novelty of this therapeutic approach, the available evidence may be influenced by publication bias and early optimism, and long-term mechanistic and clinical outcome data remain limited

doi: 10.1016/j.brainres.2015.09.035, PMID: [DOI] [PubMed] [Google Scholar] 111.Yuan Z, Li D, Feng P, Xue G, Ji C, Li G, et al

Klausen MK, et al