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The Wnt/-catenin signaling pathway is involved in the regulation of central nervous system angiogenesis and the expression of BBB-specific transporter molecules, promoting the formation of capillary TJ proteins [94,95,96]
According to NICE guidance (NG28), patients on GLP-1 receptor agonists should be reviewed regularly, with continuation based on specific HbA1c reduction and weight loss targets at around 6 months of treatment
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Accessed April 5, 2026
